FDA-approved indications for KEYTRUDA

KEYTRUDA is a prescription medicine used to treat:

• a kind of skin cancer called melanoma. It may be used when your melanoma has spread or cannot be removed by surgery (advanced melanoma).
• a kind of lung cancer called non–small cell lung cancer (NSCLC).
• • It may be used alone as your first treatment when your lung cancer has spread (advanced NSCLC) and tests positive for “PD-L1” and your tumor does not have an abnormal “EGFR” or “ALK” gene.
  • It may also be used alone for advanced NSCLC if you have tried chemotherapy that contains platinum and it did not work or is no longer working and your lung cancer tests positive for “PD-L1” and, if your tumor has an abnormal “EGFR” or “ALK” gene, you have also received an “EGFR” or “ALK” inhibitor medicine that did not work or is no longer working.
  • It may also be used with the chemotherapy medicines pemetrexed and carboplatin as your first treatment for advanced NSCLC when it is a type of lung cancer called “nonsquamous.”
• a kind of cancer called head and neck squamous cell cancer (HNSCC). It may be used when your HNSCC has returned or spread and you have received chemotherapy that contains platinum and it did not work or is no longer working.
• a kind of cancer called classical Hodgkin lymphoma (cHL). KEYTRUDA may be used for cHL in adults and children when you have tried a treatment and it did not work orwhen your cHL has returned after you received 3 or more types of treatment.
• a kind of bladder or urinary tract cancer when it has spread or cannot be removed by surgery (advanced urothelial cancer) andyou are not able to receive chemotherapy that contains a medicine called cisplatin, oryou have received chemotherapy that contains platinum, and it did not work or is no longer working.
• a kind of cancer that is shown by a laboratory test to be a microsatellite instability-high (MSI‑H) or a mismatch repair deficient (dMMR) solid tumor. KEYTRUDA may be used in adults and children to treat:
• • cancer that has spread or cannot be removed by surgery (advanced cancer), and
  • has progressed following treatment, and you have no satisfactory treatment options, or
  • you have colon or rectal cancer, and you have received chemotherapy with fluoropyrimidine, oxaliplatin, and irinotecan but it did not work or is no longer working.
• It is not known if KEYTRUDA is safe and effective in children with MSI-H cancers of the brain or spinal cord (central nervous system cancers).
• a kind of stomach cancer called gastric or gastroesophageal junction (GEJ) adenocarcinoma that tests positive for “PD‑L1.” KEYTRUDA may be used when your stomach cancer:
• • has returned or spread (advanced gastric cancer), and
  • you have received 2 or more types of chemotherapy including fluoropyrimidine and chemotherapy that contains platinum, and it did not work or is no longer working, and
  • if your tumor has an abnormal “HER2/neu” gene, you also received a HER2/neu‑targeted medicine and it did not work or is no longer working.

PD-L1 = programmed death ligand 1;
EGFR = epidermal growth factor receptor;
ALK = anaplastic lymphoma kinase;
HER2/neu = human epidermal growth factor receptor 2.

Donations to Bank Account

DKB Bank
BIC: BYLADEM1001
IBAN: DE19 1203 0000 1010 9317 54
Kennwort/Remark: Gössl
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International

Beneficiary : Gössl
Beneficiary spelling in ENGLISH : Gossl
Beneficiary Address :Room 330-331, 121 Yuan Rd. Haishu, Zhejiang 315010 NINGBO
Account Number IBAN: DE19 1203 0000 1010 9317 54
Account Number beneficiary : 1010 9317 54
Bank Name: Deutsche Kreditbank Aktiengesellschaft
Bank Address: Street: Taubenstraße 7-9
City; 10117 Berlin
Country; Germany

SWIFT / BIC: BYLADEM1001
Bank Lead Number: 120 300 00
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